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Hotels in Santee

Enjoy your stay and find the best Hotels in Santee at affordable prices

Searching for a hotel in Santee (South Carolina)? You will find a wide selection of hotels in Santee and the surrounding region at great rates, starting from $46.75 per night. From cheap budget hotels to family hotels and premium hotels for business travel and more upscale. Choose a hotel for more info about the offer.

Hotels in Santee and region (30 miles)
Holiday Inn Santee, an IHG Hotel in Santee, USA

Holiday Inn Santee, an IHG Hotel

Hotel in Santee, South Carolina , 139 Bradford Boulevard
Holiday Inn Santee is located in Santee and 35 km from Orangeburg city centre.
  • Parking
  • Restaurant
  • Pets allowed
  • Fitness centre
  • Family rooms

Good 94 Reviews 7.9

from $169.15 Show details »

Comfort Inn & Suites Santee I-95 in Santee, USA

Comfort Inn & Suites Santee I-95

Hotel in Santee, South Carolina , 221 Britain Street
Located off Interstate 95 in the heart of one of South Carolina’s premier golfing destinations, the Comfort Inn & Suites in Santee offers easy acces...
  • Parking
  • Outdoor pool
  • Swimming pool
  • Swimming Pool

Good 306 Reviews 7.4

from $115.97 Show details »

Lake Marion Inn in Santee, USA

Lake Marion Inn

Motel in Santee, South Carolina , 628 Bass Drive
Lake Marion Inn is offering accommodation in Santee.
  • Parking
  • Pets allowed
  • Shower
  • Bath
  • TV

Passable 83 Reviews 5.4

from $59.99 Show details »

Baymont by Wyndham Santee in Santee, USA

Baymont by Wyndham Santee

Motel in Santee, South Carolina , 249 Britain Street
Baymont by Wyndham Santee is a 2-star property located in Santee.
  • Parking
  • Pets allowed
  • Family rooms

Good 937 Reviews 7.4

from $79.99 Show details »

Hampton Inn Santee-I-95 in Santee, USA

Hampton Inn Santee-I-95

Hotel in Santee, South Carolina , 9060 Old Number Six Highway
Just off Interstate 95, this Santee hotel offers rooms with free Wi-Fi and a flat-screen TV.
  • Parking
  • Pets allowed
  • Fitness centre
  • Family rooms
  • Outdoor pool

Superb 539 Reviews 9.2

from $155.86 Show details »

Rodeway Inn Santee I-95 in Santee, USA

Rodeway Inn Santee I-95

Hotel in Santee, South Carolina , 123 Mall St. 
This Rodeway Inn Santee I-95 is located off Interstate 95 and is 3 km from Santee State Park, where guests can fish in Lake Marion.
  • Parking
  • Outdoor pool
  • Kid meals
  • Kid-friendly buffet
  • Swimming pool

Passable 255 Reviews 5.4

from $89.96 Show details »

Best Western PLUS Santee Inn in Santee, USA

Best Western PLUS Santee Inn

Hotel in Santee, South Carolina , 9059 Old Number Six Highway
Best Western PLUS Santee Inn is a 3-star property situated in Santee.
  • Parking
  • Pets allowed
  • Outdoor pool
  • Swimming pool
  • Swimming Pool

Very good 701 Reviews 8.4

from $111.46 Show details »

Fairfield Inn & Suites Santee in Santee, USA

Fairfield Inn & Suites Santee

Hotel in Santee, South Carolina , 9074 Old Number Six Highway
Fairfield Inn & Suites Santee has free bikes, outdoor swimming pool, a fitness centre and shared lounge in Santee.
  • Parking
  • Fitness centre
  • Family rooms
  • Allergy-free room
  • Outdoor pool

Superb 312 Reviews 9.2

from $142.00 Show details »

Red Roof Inn Santee in Santee, USA

Red Roof Inn Santee

Motel in Santee, South Carolina , 9091 Old Highway 6
Featuring free WiFi, this pet-friendly Red Roof Inn Santee is located off Interstate 95 just 10 minutes’ drive from Santee State Park.
  • Parking
  • Pets allowed

Pleasant 278 Reviews 6.7

from $66.99 Show details »

Super 8 by Wyndham Santee in Santee, USA

Super 8 by Wyndham Santee

Hotel in Santee, South Carolina , 9125 Old Highway 6
Super 8 by Wyndham Santee is a 2-star property situated in Santee.
  • Parking
  • Pets allowed
  • Family rooms
  • Allergy-free room
  • Outdoor pool

Pleasant 175 Reviews 6.3

from $75.00 Show details »

Econo Lodge in Santee, USA

Econo Lodge

Hotel in Santee, South Carolina , 9112 Old Number 6 Highway
Located in the heart of one of South Carolina’s premiere golfing destinations, the Econo Lodge in Santee, SC makes visiting nearby attractions like ...
  • Pets allowed

Okay 43 Reviews 6.0

from $65.20 Show details »

Travelodge by Wyndham Santee in Santee, USA

Travelodge by Wyndham Santee

Hotel in Santee, South Carolina , 9117 Old Number 6 Hwy
Conveniently located off of Interstate 95, in the heart of one of South Carolina’s premiere golfing destinations, this hotel is located in Santee, S...
  • Parking
  • Pets allowed
  • Family rooms
  • Outdoor pool
  • Swimming pool

Pleasant 380 Reviews 6.3

from $59.99 Show details »

Days Inn by Wyndham Orangeburg South in Orangeburg, USA

Days Inn by Wyndham Orangeburg South

Hotel in Orangeburg near Santee, South Carolina , 3402 Five Chop Road
Days Inn by Wyndham Orangeburg South is a 2-star property set in Orangeburg.
  • Parking
  • Pets allowed
  • Family rooms
  • Outdoor pool
  • Swimming pool

Pleasant 470 Reviews 6.0

from $49.23 Show details »

Peach Tree Inn in Saint George, USA

Peach Tree Inn

Motel in Saint George near Santee, South Carolina , 111 Conners Drive
This hotel is a 10-minute drive from downtown Saint George, South Carolina and 10 miles from Saint George Country Club.
  • Parking
  • Pets allowed
  • Tea/Coffee maker
  • Shower
  • Bath

Pleasant 138 Reviews 6.1

from $70.00 Show details »

Sunset Inn Manning in Manning, USA

Sunset Inn Manning

Motel in Manning near Santee, South Carolina , 5932 Alex Harvin Highway
Located in Manning, South Carolina, this motel features an outdoor pool.
  • Parking
  • Family rooms

Pleasant 31 Reviews 6.1

from $46.75 Show details »

Ashburn Inn Of Manning in Manning, USA

Ashburn Inn Of Manning

Hotel in Manning near Santee, South Carolina , 5973 ALEX HARVIN HWY
Ashburn Inn Of Manning provides air-conditioned accommodation in Manning.
  • Parking
  • Pets allowed
  • Allergy-free room
  • Shower
  • Bath

Disappointing 22 Reviews 4.0

from $55.00 Show details »

OYO Hotel Manning SC in Manning, USA

OYO Hotel Manning SC

Hotel in Manning near Santee, South Carolina , Carolina Inn, 5342 Alex Harvin Hwy
OYO Hotel Manning SC features air-conditioned accommodation in Manning.
  • Parking
  • Pets allowed
  • Tea/Coffee maker
  • Safety deposit box
  • TV

Poor 53 Reviews 3.3

from $62.00 Show details »

Countryside Inn in Harleyville, USA

Countryside Inn

Motel in Harleyville near Santee, South Carolina , 188 Judge Street
The Countryside Inn is located off Interstate 26 in Harleyville South Carolina.
  • Parking
  • Pets allowed
  • Family rooms

Okay 56 Reviews 5.9

from $70.00 Show details »

Fairfield Inn Orangeburg in Orangeburg, USA

Fairfield Inn Orangeburg

Hotel in Orangeburg near Santee, South Carolina , 663 Citadel Road
This hotel is located at the junction of Interstate 26 and Highway 601.
  • Parking
  • Fitness centre
  • Outdoor pool
  • Swimming pool
  • Swimming Pool

Good 270 Reviews 8.0

from $93.00 Show details »

SpringHill Suites by Marriott Orangeburg in Orangeburg, USA

SpringHill Suites by Marriott Orangeburg

Hotel in Orangeburg near Santee, South Carolina , 675 Citadel Road
SpringHill Suites by Marriott Orangeburg is a 3-star property located in Orangeburg.
  • Parking
  • Fitness centre
  • Electric vehicle charging station

Fabulous 663 Reviews 8.7

from $104.72 Show details »

Tru By Hilton Orangeburg in Orangeburg, USA

Tru By Hilton Orangeburg

Hotel in Orangeburg near Santee, South Carolina , 739 Citadel Road
Tru By Hilton Orangeburg is a 3-star property situated in Orangeburg.
  • Parking
  • Pets allowed
  • Fitness centre

Fabulous 415 Reviews 8.8

from $118.18 Show details »

Hampton Inn & Suites Orangeburg, SC in Orangeburg, USA

Hampton Inn & Suites Orangeburg, SC

Hotel in Orangeburg near Santee, South Carolina , 749 Citadel Road
This Orangeburg, South Carolina Hampton Inn & Suites features an outdoor pool, free WiFi, and free breakfast.
  • Parking
  • Pets allowed
  • Fitness centre
  • Family rooms
  • Outdoor pool

Fabulous 244 Reviews 9.0

from $148.01 Show details »

Days Inn by Wyndham Orangeburg in Orangeburg, USA

Days Inn by Wyndham Orangeburg

Motel in Orangeburg near Santee, South Carolina , 3691 Saint Matthews Road
Located off Interstate 26, this South Carolina motel offers guests a grab and go breakfast and free property-wide WiFi.
  • Parking
  • Family rooms
  • Allergy-free room

Disappointing 214 Reviews 4.9

from $53.55 Show details »

Travelodge by Wyndham Orangeburg in Orangeburg, USA

Travelodge by Wyndham Orangeburg

Motel in Orangeburg near Santee, South Carolina , 3620 St Matthews Road
Located off Interstate 26, this South Carolina motel is 5 miles from Aquatic Park.
  • Parking

Good 282 Reviews 7.4

from $55.30 Show details »

Super 8 by Wyndham Orangeburg Near I-26 in Orangeburg, USA

Super 8 by Wyndham Orangeburg Near I-26

Hotel in Orangeburg near Santee, South Carolina , 3608 St Matthews Rd
Just 7 minutes’ drive from South Carolina State University, Super 8 Orangeburg Near I-26 offers free WiFi in every room.
  • Parking
  • Pets allowed

Pleasant 402 Reviews 6.3

from $66.00 Show details »

Number of Hotels in Santee 40
Number of guest ratings 4214
Average price per night $85.81
Lowest price per night $46.75
Highest price per night $169.15

Most popular Hotels in Santee

The most popular Hotels in Santee based on average guest rating (Top 10).

Cheapest Hotels in Santee

The cheapest Hotels in Santee based on room rate per night (Top 10).

Most booked Hotels in Santee

The most booked Hotels in Santee based on popularity with guests (Top 10).

How to find the best hotel in Santee (South Carolina)

Finding the best hotel in Santee depends on your individual needs and preferences. First, consider your budget. Deciding how much you are willing to spend can help you narrow down your search and avoid overspending. Keep in mind that higher prices may not always equate to better quality or value.

Next, think about the location. Do you want to stay in the heart of Santee, or would you prefer a quieter area outside of town? Consider factors like proximity to attractions, transportation, and safety when choosing a location.

After that, consider the type of hotel you want to stay in. Do you prefer a boutique hotel with personalized service, or a large chain hotel with more amenities? Think about whats most important to you, whether it is a pool, a gym, or a great restaurant.

It is also important to read reviews from other travelers to get an idea of the hotels reputation. Look for comments about cleanliness, service, and overall experience to get a better sense of what to expect.

Don't be afraid to contact the hotel directly with any questions or concerns. A good hotel should be happy to answer your questions and make your stay as comfortable as possible.

Hotels in Santee - which one to choose?

One of the most common types of hotels in Santee and surrounding region are budget or economy hotels, who offer affordable accommodation for travelers on a tight budget, and extended-stay hotels, which are designed for guests who need to stay for an extended period of time, such as business travelers or those relocating to a new city.

Another popular type of hotel is the boutique hotel. These hotels are smaller in size and typically feature unique and personalized decor and amenities, often designed to appeal to a specific target market or theme. Boutique hotels in Santee are often independently owned and operated, and they are known for their distinctive character and personalized service.

If you want the carefree package maybe the luxury hotel in Santee ist the right choice for you. These hotels are known for their high-end amenities and exceptional service, and are often located in prime locations such as city centers or scenic destinations. Luxury hotels typically feature upscale restaurants, fitness centers, spas, and other lavish facilities, and they are designed to cater to guests who are seeking a luxurious and indulgent experience.

Resort hotels are another common type of accommodation, particularly in tropical and beach destinations. These hotels offer a wide range of amenities, including pools, spas, restaurants, and outdoor activities such as water sports and golf. They are designed to provide guests with a complete vacation experience, with everything they need to relax and have fun in one location.

Accommodation data and pictures provided by Booking.com